Umberto Tosi, MD, a PGY-5 resident at Weill Cornell Medicine, was awarded second place for his research presentation at the New York Society of Neurosurgery's annual Resident Research Night last week. Dr. Tosi’s presentation, “A Novel Therapeutic Monoclonal Antibody for Inhibition of NOTCH Signaling to Prolong Survival in High-Grade Glioma Models,” reported on work he is conducting in the laboratory of Dr. Viviane Tabar, chair of neurosurgery at Memorial Sloan Kettering Cancer Center. Dr. Tosi and colleagues are investigating a novel monoclonal antibody against ADAM10, a protein responsible for NOTCH signaling activation in high-grade gliomas.
Dr. Tosi was one of eight residents invited to present their work at Resident Research Night. One resident each from Weill Cornell Medicine, Columbia, NYU Langone, Montefiore, Mount Sinai, Northwell Health, Rutgers, and Westchester Medical Center presented research. (Weill Cornell Medicine residents conduct research and treat patients at both NewYork-Presbyterian and MSKCC.) Residents present basic or clinical research to a panel of neurosurgical judges, then answer questions from the panel before a winner is announced.
This is the second year in a row that Weill Cornell Medicine neurosurgical residents have been honored at Resident Research Night. Last year Dr. Alexandra Giantin-Larsen was honored for her work on liquid biopsies for brainstem gliomas, also conducted at MSKCC.
Dr. Tosi’s work was also honored earlier this year at the annual meeting of the Congress of Neurological Surgeons, where he won the KLS Martin Tumor Award (see news item about that award).