Advances in Glioblastoma Operative Techniques.

Numerous studies have demonstrated the importance of gross total resection in improving patient survival in glioblastoma (GBM). Advances in surgical tools and techniques such as intra-operative imaging, fluorescent agents, and functional imaging sequences are allowing for better identification of tumor borders and vital eloquent cortex in order to safely achieve higher rates of complete resections. Furthermore, due to the limits of surgical resection alone, new minimally invasive techniques for treatment of GBM are under development. These advances are crucial for improving neurosurgical care and outcomes in this difficult patient population.