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Brachytherapy for meningiomas.

TitleBrachytherapy for meningiomas.
Publication TypeJournal Article
Year of Publication2020
AuthorsMagill ST, Schwartz TH, Theodosopoulos PV, McDermott MW
JournalHandb Clin Neurol
Volume170
Pagination303-307
Date Published2020
ISSN0072-9752
Abstract

Interstitial intracranial radiotherapy implants, or brachytherapy, is an adjuvant option for treatment of recurrent high-grade meningiomas after resection. The implants are placed in the resection cavity following tumor resection. The most commonly used isotope is Iodine-125 (I-125). While there are no controlled studies comparing treatment of meningiomas with or without brachytherapy, several case series report good long-term survival, suggesting that this may be a useful adjuvant for recurrent high-grade tumors. Complications can occur including radiation necrosis, impaired wound healing, hydrocephalus and infection. In the future, new isotopes are being explored that may have fewer complications and better safety profiles.

DOI10.1016/B978-0-12-822198-3.00049-5
Alternate JournalHandb Clin Neurol
PubMed ID32586503