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Endonasal surgery for suprasellar germ cell tumors: two cases and review of the literature.

TitleEndonasal surgery for suprasellar germ cell tumors: two cases and review of the literature.
Publication TypeJournal Article
Year of Publication2019
AuthorsArnaout MM, Gerges MM, Cummock MD, Asri ACherif El, Greenfield JP, Anand VK, Schwartz TH
JournalActa Neurochir (Wien)
Volume161
Issue8
Pagination1699-1704
Date Published2019 08
ISSN0942-0940
KeywordsAdolescent, Adult, Humans, Male, Natural Orifice Endoscopic Surgery, Neoplasms, Germ Cell and Embryonal, Nose, Pituitary Neoplasms
Abstract

Germ cell tumors are rare malignant tumors frequently located in the suprasellar region. Definitive treatment is chemotherapy and radiation. However, in some circumstances, surgery is indicated for biopsy or resection. There are limited reports of the role of the endonasal endoscopic approach (EEA) in the management of this tumor. We present two cases in which EEA was utilized for successful management of germ cell tumor. The most challenging aspect of germ cell tumor management for the treating physician is knowing the proper indications for surgery. In this paper, we highlight two specific instances, namely diagnosis and tumor refractory to chemoradiation. Given the suprasellar location, EEA is an ideal approach.

DOI10.1007/s00701-019-03969-3
Alternate JournalActa Neurochir (Wien)
PubMed ID31214781