| Title | Preoperative Narcotic Use, Impaired Ambulation Status, and Increased Intraoperative Blood Loss Are Independent Risk Factors for Complications Following Posterior Cervical Laminectomy and Fusion Surgery. | 
| Publication Type | Journal Article | 
| Year of Publication | 2019 | 
| Authors | Badiee RK, Chan AK, Rivera J, Molinaro A, Doherty BR, K Riew D, Chou D, Mummaneni PV, Tan LA | 
| Journal | Neurospine | 
| Volume | 16 | 
| Issue | 3 | 
| Pagination | 548-557 | 
| Date Published | 2019 Sep | 
| ISSN | 2586-6583 | 
| Abstract | OBJECTIVE: This retrospective cohort study seeks to identify risk factors associated with complications following posterior cervical laminectomy and fusion (PCLF) surgery. METHODS: Adults undergoing PCLF from 2012 through 2018 at a single center were identified. Demographic and radiographic data, surgical characteristics, and complication rates were compared. Multivariate logistic regression models identified independent predictors of complications following surgery. RESULTS: A total of 196 patients met the inclusion criteria and were included in the study. The medical, surgical, and overall complication rates were 10.2%, 23.0%, and 29.1% respectively. Risk factors associated with medical complications in multivariate analysis included impaired ambulation status (odds ratio [OR], 2.27; p=0.02) and estimated blood loss over 500 mL (OR, 3.67; p=0.02). Multivariate analysis revealed preoperative narcotic use (OR, 2.43; p=0.02) and operative time (OR, 1.005; p=0.03) as risk factors for surgical complication, whereas antidepressant use was a protective factor (OR, 0.21; p=0.01). Overall complication was associated with preoperative narcotic use (OR, 1.97; p=0.04) and higher intraoperative blood loss (OR, 1.0007; p=0.03). CONCLUSION: Preoperative narcotic use and estimated blood loss predicted the incidence of complications following PCLF for CSM. Ambulation status was a significant predictor of the development of a medical complication specifically. These results may help surgeons in counseling patients who may be at increased risk of complication following surgery. | 
| DOI | 10.14245/ns.1938198.099 | 
| Alternate Journal | Neurospine | 
| PubMed ID | 31607087 | 
| PubMed Central ID | PMC6790747 | 
| Grant List | UL1 TR001863 / TR / NCATS NIH HHS / United States / / UCSF School of Medicine / | 
 
          