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Spontaneous regression of a clival chordoma. Case report.

TitleSpontaneous regression of a clival chordoma. Case report.
Publication TypeJournal Article
Year of Publication2020
AuthorsBander ED, Kocharian G, Liechty B, Tsiouris AJ, Schwartz TH
JournalActa Neurochir (Wien)
Volume162
Issue2
Pagination433-436
Date Published2020 02
ISSN0942-0940
KeywordsAged, Chordoma, Cranial Fossa, Posterior, Female, Humans, Magnetic Resonance Imaging, Neoplasm Regression, Spontaneous, Plant Extracts, Self Administration, Skull Base Neoplasms
Abstract

In this case report, we present a rare and previously unreported case of spontaneous regression of a histologically consistent clival chordoma. At the time of diagnosis, imaging demonstrated a T2 hyperintense and T1 isointense midline skull base mass, centered in the nasopharynx, with scalloping of the ventral clivus consistent with a chordoma measuring 3.1 × 1.9 × 3.0 cm (8.84 cm). On pre-operative imaging 2 months later, with no intervening therapy, the mass had regressed by 61.7% to a size of 2.3 × 2.1 × 1.4 cm (3.38 cm). The patient self-administered several herbal supplements and animal oils which may have contributed to tumor regression. The purpose of this report is to document this rare occurrence and provide a comprehensive description of the case details and list of the various medications, herbs, and supplements used prior to this rare event.

DOI10.1007/s00701-019-04107-9
Alternate JournalActa Neurochir (Wien)
PubMed ID31713157