For COVID-19 vaccine updates, please review our information guide. For patient eligibility and scheduling availability, please visit VaccineTogetherNY.org.

Pediatric Suprasellar Tumors.

TitlePediatric Suprasellar Tumors.
Publication TypeJournal Article
Year of Publication2016
AuthorsMcCrea HJ, George E, Settler A, Schwartz TH, Greenfield JP
JournalJ Child Neurol
Volume31
Issue12
Pagination1367-76
Date Published2016 10
ISSN1708-8283
KeywordsBrain Neoplasms, Central Nervous System Cysts, Child, Humans
Abstract

The various childhood suprasellar tumors, while pathologically distinct, present similar clinical and surgical challenges as a result of their common anatomic location. These lesions are in close proximity to or may invade the optic nerve and chiasm, pituitary gland and infundibulum, hypothalamus, and third ventricle, leading to presenting features including visual field loss, impairment in visual acuity, endocrine dysfunction, and hydrocephalus. Though many suprasellar lesions are relatively benign in pathology, treatment may be complicated by high surgical morbidity resulting from damage to the hypothalamic-pituitary axis. Here we review the most frequent pediatric lesions occurring in the suprasellar region: craniopharyngioma, chiasmatic glioma, germ cell tumor, Rathke cleft and arachnoid cysts, pituitary adenoma, and histiocytosis. This review outlines both common presenting features and differentiating aspects of these lesions. It also includes classic radiographic presentations and treatment considerations for each lesion.

DOI10.1177/0883073815620671
Alternate JournalJ Child Neurol
PubMed ID26676303